Stefan J Marciniak Selected Research

Neuroserpin

12/2015	Interactions between N-linked glycosylation and polymerisation of neuroserpin within the endoplasmic reticulum.
11/2013	Sterol metabolism regulates neuroserpin polymer degradation in the absence of the unfolded protein response in the dementia FENIB.
1/2013	Endoplasmic reticulum dysfunction in neurological disease.
10/2011	Unravelling the twists and turns of the serpinopathies.
3/2011	Characterisation of serpin polymers in vitro and in vivo.
1/2011	The serpinopathies studying serpin polymerization in vivo.
8/2009	Endoplasmic reticulum-associated degradation (ERAD) and autophagy cooperate to degrade polymerogenic mutant serpins.
7/2009	Neuroserpin polymers activate NF-kappaB by a calcium signaling pathway that is independent of the unfolded protein response.
5/2009	alpha1-Antitrypsin deficiency, chronic obstructive pulmonary disease and the serpinopathies.

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Stefan J Marciniak Research Topics

Disease

8	Dementia (Dementias) 12/2015 - 05/2009
7	Neoplasms (Cancer) 04/2024 - 05/2014
6	Fibrosis (Cirrhosis) 04/2022 - 05/2009
6	Brain Diseases (Brain Disorder) 11/2013 - 07/2009
5	Lung Diseases (Lung Disease) 09/2023 - 01/2016
5	Liver Diseases (Liver Disease) 10/2018 - 09/2010
4	Mesothelioma 05/2024 - 11/2020
4	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 02/2011
3	Malignant Mesothelioma 01/2023 - 04/2016
3	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2022 - 06/2017
3	Hypoxia (Hypoxemia) 01/2021 - 06/2014
3	Pneumothorax 11/2020 - 12/2015
3	Emphysema 06/2015 - 03/2011
2	Chronic Obstructive Pulmonary Disease (COPD) 01/2016 - 05/2009
2	Necrosis 11/2013 - 02/2008
2	Hepatocellular Carcinoma (Hepatoma) 05/2013 - 01/2011
2	Neonatal hemochromatosis 05/2013 - 01/2011
2	Diabetes Mellitus 07/2011 - 10/2006
1	Hereditary Hemorrhagic Telangiectasia 03/2024
1	Interstitial Lung Diseases (Interstitial Lung Disease) 09/2023
1	Hypersensitivity (Allergy) 04/2022
1	Pulmonary Arterial Hypertension 01/2022
1	Asthma (Bronchial Asthma) 01/2022
1	Inflammation (Inflammations) 01/2021
1	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2021
1	Malignant Pleural Effusion 01/2021
1	Mediastinal Emphysema (Pneumomediastinum) 11/2020
1	COVID-19 11/2020
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2020
1	Body Weight (Weight, Body) 01/2019
1	Cicatrix (Scar) 01/2019
1	Asphyxia (Suffocation) 01/2019
1	Proteostasis Deficiencies 01/2017
1	Pneumonia (Pneumonitis) 12/2016
1	Autism Spectrum Disorder 02/2016
1	Liver Failure 01/2016
1	Familial encephalopathy with neuroserpin inclusion bodies 12/2015
1	Bacterial Infections (Bacterial Infection) 06/2015
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2015
1	Pericardial Effusion 12/2014
1	Paralysis (Palsy) 01/2014
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 11/2013
1	Enteritis 11/2013
1	Ileitis 11/2013
1	Pulmonary Hypertension 04/2013
1	Right Ventricular Hypertrophy 04/2013
1	Starvation 03/2013
1	Stroke (Strokes) 01/2013
1	Virus Diseases (Viral Diseases) 01/2012

Drug/Important Bio-Agent (IBA)

11	PolymersIBA 04/2022 - 05/2009
10	Proteins (Proteins, Gene)FDA Link 01/2023 - 07/2011
9	NeuroserpinIBA 12/2015 - 05/2009
4	AsbestosIBA 10/2021 - 04/2016
3	SmokeIBA 01/2021 - 06/2017
3	Peptides (Polypeptides)IBA 01/2014 - 01/2013
2	Surface-Active Agents (Surfactants)IBA 09/2023 - 01/2022
2	Protein CIBA 09/2023 - 01/2022
2	Prokaryotic Initiation Factor-2IBA 01/2017 - 03/2013
2	SerpinsIBA 12/2015 - 02/2008
2	Amyloid (Amyloid Fibrils)IBA 12/2013 - 01/2013
2	Amino Acids FDA Link 03/2013 - 01/2012
1	ZirconiumIBA 04/2024
1	Pemetrexed (MTA)FDA Link 04/2024
1	Metal-Organic FrameworksIBA 04/2024
1	DNA (Deoxyribonucleic Acid)IBA 03/2024
1	Nonsense Codon (Nonsense Mutation)IBA 03/2024
1	EndoglinIBA 03/2024
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2022
1	CytokinesIBA 01/2022
1	GoldIBA 11/2020
1	Flavin-Adenine Dinucleotide (FAD)IBA 01/2020
1	Presenilin-1IBA 01/2020
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2020
1	Glucose (Dextrose)FDA LinkGeneric 01/2020
1	CalciumIBA 01/2020
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2019
1	Peptide Initiation Factors (Initiation Factor)IBA 01/2019
1	Environmental Pollutants (Pollutants, Environmental)IBA 06/2017
1	Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA 12/2016
1	NeuroliginsIBA 02/2016
1	Peptide Hydrolases (Proteases)FDA Link 01/2016
1	AsparagineIBA 12/2015
1	Transforming Growth Factor-beta Type II ReceptorIBA 12/2015
1	Toll-Like Receptors (Toll-Like Receptor)IBA 06/2015
1	Leukocyte Elastase (Neutrophil Elastase)IBA 06/2015
1	SterolsIBA 11/2013
1	Inositol (Myoinositol)IBA 11/2013
1	EnzymesIBA 11/2013
1	Transcription Factors (Transcription Factor)IBA 11/2013
1	Chloroquine (Aralen)FDA LinkGeneric 04/2013
1	MonocrotalineIBA 04/2013
1	Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA 04/2013
1	Phosphotransferases (Kinase)IBA 03/2013

Therapy/Procedure

7	Therapeutics 05/2024 - 03/2011
2	Drug Therapy (Chemotherapy) 04/2024 - 10/2021
1	Catheters 01/2021
1	Pleurodesis 01/2021
1	Extracorporeal Membrane Oxygenation 11/2020
1	Precision Medicine 01/2018
1	Liver Transplantation 01/2016